Ryan Toedebusch

Ryan Toedebusch

Associate Project Scientist

Surgical & Radiological Sciences


Education
2010, BS, University of Missouri, Columbia, Missouri
2015, PhD, University of Missouri, Columbia, Missouri
Active Research Grants
Principal Investigator, Characterization of metabolic control of glioma stem cell growth kinetics, (Principal Investigator), CCAH
Co-Investigator, Characterization of canine glioma-associated microglia, Christine Toedebusch (Principal Investigator), CCAH
Assistant Researcher, Mechanism of pro-tumorigenic glioma-associated microglia: characterization of the role of olfactomedin-like 3, Christine Toedebusch (Principal Investigator), UC-Davis Comparative Cancer Center
Most Recent Five Book Chapters
2015 Booth FW, Ruegsegger GN, Toedebusch RG, Zhen Y : Endurance exercise and the regulation of skeletal muscle metabolism, , Prog Mol Biol Transl Sci, . 129-151.
Ten Recent Publications

2019
Heese AJ, Roberts CK, Hofheins JC, Brown JD, Ruegsegger GN, Toedebusch RG, Booth FW
Rats Selectively Bred for High Voluntary Physical Activity Behavior are Not Protected from the Deleterious Metabolic Effects of a Western Diet When Sedentary

2018
Toedebusch RG, Belenchia A, Pulakat L
Cell-Specific Protective Signaling Induced by the Novel AT2R-Agonist NP-6A4 on Human Endothelial and Smooth Muscle Cells

2018
Belenchia AM, Gavini MP, Toedebusch RG, DeMarco VG, Pulakat L
Comparison of Cardiac miRNA Transcriptomes Induced by Diabetes and Rapamycin Treatment and Identification of a Rapamycin-Associated Cardiac MicroRNA Signature

2018
Toedebusch RG, Belenchia A, Pulakat L
Diabetic Cardiomyopathy: Impact of Biological Sex on Disease Development and Molecular Signatures

2017
Lum Naihe K, Toedebusch RG, Mahmood A, Bajwa J, Carmack T, Kumar SA, Ardhanari S, DeMarco V, Emter CA, Pulakat L
Cardiovascular disease progression in female Zucker Diabetic Fatty rats occurs via unique mechanisms compared to males

2017
Booth FW, Roberts CK, Thyfault JP, Ruegsegger GN, Toedebusch RG
Role of inactivity in chronic diseases: evolutionary insight and pathophysiological mechanisms

2017
Ruegsegger GN, Toedebusch RG, Braselton JF, Childs TE, Booth FW
Left ventricle transcriptomic analysis reveals connective tissue accumulation associates with initial age-dependent decline in Vo2peak from its lifetime apex

2016
Toedebusch RG, Ruegsegger GN, Braselton JF, Heese AJ, Hofheins J, Childs TE, Thyfault J, Booth FW
AMPK agonist AICAR delays the initial decline in lifetime-apex Vo2peak while voluntary wheel running fails to delay it initial decline in female rats

2016
Ruegsegger GN, Toedebusch RG, Childs TE, Grigsby KB, Booth FW
Loss of Cdk5 function in the nucleus accumbens decreases wheel running and may mediate age-related declines in voluntary physical activity

2015
Ruegsegger GN, Company JM, Toedebusch RG, Roberts C, Roberts MD, Booth FW
Rapid alterations in perirenal adipose tissue transcriptomic networks with cessation of voluntary running